Health Supplement Stores NAICS 456191

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Industry Summary
The 5,500 health supplement stores in the US sell vitamins, nutritional supplements, body enhancing supplements, and related products. Companies may also carry additional product categories associated with healthy lifestyles, including organic/natural foods and personal care products; diet and weight management supplements; and specialty pet foods. The industry includes national and regional chains, franchises, and independent operators. Large retailers often stock several thousand stock keeping units (SKUs) in each store, across multiple categories and brands.
Consumer Skepticism
The world of health supplements is fraught with conflicting information.
Fads And Trends
Driven by new product proliferation, the health supplement industry is subject to fads and trends, which can cause uneven demand and cash flow.
Recent Developments
May 28, 2025 - Cooler Growth Expected
- The US health supplement stores industry is projected to grow at a 3.71% CAGR from 2025 to 2029, slower than the overall economy's projected growth, according to a forecast from Inforum and the Interindustry Economic Research Fund, Inc. The retail and wholesale sectors are driven by consumer spending, along with expenditure by businesses and government. Retail spending could soften with the growth of spending on consumer services. A factor that may limit consumer spending is higher tariffs on consumer goods. In 2025 and into the forecast period, real disposable income may be supported by continuing nominal wage growth, lower inflation rates, and higher employment levels. Lower inflation supports a moderate increase of real disposable income by about 2% in 2025 and 1.9% in 2026. Real income could suffer if prices rise due to tariff implementation.
- According to a new report in Retail Dive, the retail sector had 64,319 job cuts in the first four months of 2025, a nearly 300% increase year over year, and was the second-leading industry in job cuts. The Challenger, Gray & Christmas report found retail job cuts were up almost 80% year over year in April 2025, reaching 7,235. According to Andrew Challenger, an SVP at the consulting firm, “Generally, companies are citing the economy and new technology. Employers are slow to hire and limiting hiring plans as they wait and see what will happen with trade, supply chain, and consumer spending.” The US lost 603,000 jobs in total across all industries, the most since 2020, when over one million job cuts occurred. According to the report, nearly half of the cuts in the first four months were attributed to job eliminations by the Department of Government Efficiency (DOGE).
- Health supplement retailers may see an increase in dietary supplement prices and potential supply chain issues following new tariffs imposed by the Trump administration. The Trump administration has enacted a range of new tariffs, including tariffs on imports from China (on top of existing tariffs applied to Chinese goods), a tariff on imported steel and aluminum, and tariffs on selected imports from Canada and Mexico, among others. In an interview with SupplySide Supplement Journal, Loren Israelsen, president of the United Natural Products Alliance (UNPA), said the Chinese tariffs are most important for the dietary supplement industry, as China is the dominant supplier of both folic acid and vitamin D3 to the US. Per the UNPA, as much as 80% of raw nutraceutical ingredients on the market originate from China. During his first term, Trump raised tariffs by 7.5% on several dietary supplement ingredients, per Israelsen.
- A new survey from NOW Health Group found that supplements increasing energy levels will be a priority for consumers in 2025, according to Vitamin Retailer Magazine. The survey showed that 56% of survey respondents reported seeking supplements to boost their energy levels and keep up with their busy lives. Other top areas for supplements, according to the survey, included fitness support (56%), better sleep (36%), and weight management support (31%). More Americans are being proactive about their health, with more than half of respondents saying they are prioritizing healthy aging in their 30s or earlier.
Industry Revenue
Health Supplement Stores

Industry Structure
Industry size & Structure
The average health supplement store operates out of a single location, employs 7 workers, and generates $1.3 million annually.
- The health supplement retailing industry consists of about 5,500 firms that operate 8,600 stores, employ 36,900 workers and generate about $6.9 billion annually.
- The industry is fragmented at the bottom with some large players at the top; the top 50 companies account for about 51% of industry revenue.
- Large companies include General Nutrition Centers (GNC), Vitamin Shoppe, and Vitamin World.
- The industry includes national and regional chains, franchises, and independent operators.
Industry Forecast
Industry Forecast
Health Supplement Stores Industry Growth

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